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Columbia has a diverse economy, and its major employers include South Carolina state government, Blue Cross Blue Shield of SC, the Palmetto Health hospital system, and the University of South Carolina. SCANA, a Fortune 500 company, is located in Cayce, only about 6 miles from Bicycle City.
Other major employers in the Columbia area include Fort Jackson, the U.S. Army's largest and most active initial entry training installation, and the United Parcel Service, which operates its Southeastern Regional Hub at the Columbia Metropolitan Airport. Major manufacturers such as Michelin, CMC Steel, Honeywell, Westinghouse Electric, Union Switch & Signal, and Bose Corporation Technology have facilities in the Columbia area.
There are over 70 foreign-affiliated companies and fourteen Fortune 500 companies in the region. In 2008, the gross domestic product (GDP) of the Columbia metropolitan statistical area was $30.08 billion.